Patient centered reanalysis of trials data

2024.12.22

The group of Ulrich Mansmann just published two papers based on clinical trials data sharing: 1) "Multivariable prognostic prediction of efficacy and safety outcomes and response to fingolimod in people with relapsing-remitting multiple sclerosis"article ↗; 2) "Addressing treatment switching in the ALTA-1L trial with g-methods: exploring the impact of model specification" article ↗.

Navigating US participant data sharing requirements: implications for international clinical trials

2024.10.16

An interesting article in BMJ article ↗ we'd like to share with you.

Kick-off meeting and propaedeutic course of SHARE-CTD at Schloss Fürstenried (Munich) from 08.09.2024 to 14.09.2024

2024.09.16

The SHARE-CTD kick-off meeting and the propaedeutic course took place in person with international principal investigators, partners and doctoral students at Schloss Fürstenried (Munich) from 08.09 to 14.09.2024. The focus was on lectures and exercises around the topics Clinical Trial Design, Clinical Trial Implementation, Privacy Protection, Data Management, Evidence Synthesis, to bring the students with different university backgrounds to the same level. To compensate for this rather heavy mental fare, there were games evenings for social networking, a Munich city tour for cultural input and local/ bavarian meals for the physical well-being. The productive and diverse meeting ended with a brainstorming session and some homework for everyone involved. Now, all of us are starting the next three years of the SHARE-CDT project with a lot of hope and energy! And we are looking forward to the 1st schooling event at Reisensburg in January 2025 with all of you!

SHARE-CTD members met in Munich, at IBE, for a second face-to-face meeting to prepare several topics

2024.06.19

The meeting, in person and via web, was scheduled as a lunch-to-lunch meeting. During Day 1 (17th of June) ideas were collected as building stones for the following three SHARE-CTD training activities: Propaedeutic meeting, first schooling event and first datathon. On day 2 (18th of June), the idea puzzle came together to form a broader picture: a concept to provide our Doctoral Candidates clear and focused learning objectives along the line of Bloom’s Taxonomy: Remember, Understand, Apply, Analyse, Evaluate, Create. The meeting was moderated by Brigitte Strahwald (LMU), an expert in medical education. We are ready for the next steps: to prepare the propaedeutic course in September and to welcome our Doctoral Candidates!

Day 1

Day 2

SHARE-CTD at 8th World Conference on Research Integrity (WCRI) in Athens

2024.06.06

As part of the 8th World Conference on Research Integrity (WCRI) in Athens from 02.06.2024 to 05.06.2024 Prof. Florian Naudet (University of Rennes) will hold a symposium on the following topic: Toward responsible clinical trial data sharing practices. Within this symposium, Prof. Mansmann (Ludwig-Maximilians-University Munich) will also give a lecture on An initiative to train researchers and staff as part of the SHARE-CTD doctoral network. In addition to this lecture, three further lectures on the following topics are planned: (1) Clinical trial data sharing and the global south by Nchangwi Syntia Munung, PhD, Researcher, University of Cape Town; (2) COPE positions about management of empty promises by Daniel Kulp, PhD, senior director (American Chemical Society) COPE (chair); (3) Ethics and incentives for clinical trial data sharing by Jennifer Ellen Miller, PhD, Associate professor, Yale School of Medicine.

Further information on the symposium can be found here: wcri2024.org/symposia
Further information on the 8th WCRI can be found here: wcri2024.org

Paper published in Nature Medicine with participation of SHARE-CTD members

2024.03.25

Members of the SHARE-CTD network coauthored a comment paper published in Nature Medicine (21st of March 2024) on "Understanding the provenance and quality of methods is essential for responsible reuse of FAIR data".  nature article ↗

SHARE-CTD members met in Paris for a first face-to-face meeting, after many virtual meetings to prepare the project

2024.02.22

During the two days (February 15 and 16, 2024), we were able to meet on the premises of the French Ministry of Research in the Quartier Latin. We used the time to get a very detailed overview of the planned project activities, to discuss their interlinkages and how our project can benefit from the interaction with ongoing activities of other groups (IRISE, OSIRIS, TIER2). We also met with Christine Kubiac to discuss the role of ECRIN in our project. It was important to run through curricular scenarios in order to bring the planned research work, the concepts to be taught and the active work on data into an effective and synergistic relationship. Most importantly, we did prepare for the active selection phase for the applications received. Thanks to Prof. Dr. Bruno Falissard, a member of our scientific advisory board, for his first contact with us. Special thanks to Florian for organizing this intensive and focused meeting with the support of the Institut Universitaire de France.

The application period is over as of 1st February 2024

2024.02.01

Thanks for all the applications. The named referees can access the application system with their individual links until 07.02.2024. The applicants will be updated about the status of and decisions on their applications in due time.

Kick-off meeting and propaedeutic in September 2024 in Munich

2024.01.15

The Kick-off-meeting will take place in Munich from 08.09. to 14.09.2024 with the Partners, doctoral candidates and guest speakers. The complete program will be announced in time.

Closing date for applications is 31rd January 2024

2024.01.08

Uncompleted applications have to be completed and submitted latest by 31.01.24 in the application portal, after which the system will be available only for named referees until 07.02.2024.

Selection Board established

2024.01.08

For finalizing the recruitment process of the doctoral candidates, the Selection Board formed of all supervisors was established during the Jour Fixe meeting in January 2024.

Implementing clinical trial data sharing requires training a new generation of biomedical researchers

2024.01.08

An interesting nature medicine article ↗ we'd like to share with you.

Making data sharing the norm in medical research

2024.01.08

An interesting nature medicine article ↗ we'd like to share with you.

Data Sharing — A New Era for Research Funded by the U.S. Government

2024.01.08

An interesting article in The NEW ENGLAND JOURNAL of MEDICINE article ↗ we'd like to share with you.